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UL Research Soapbox

Research Soapbox highlights how research can make a real difference. Eileen Courtney represented TEMUL at the event, giving a short talk entitled "2D Materials…

Research Collaboration visit to Prof Boon Ooi’s Photonics Research Group

PhD student Kalani Moore spent 2 months interning at Prof Boon Ooi's Photonics research group. He has been working on low loss EELS analysis…

19th International Microscopy Congress

Members of the TEMUL group attended the 19th International Microscopy Congress held in Sydney, Australia, where they presented their latest microscopy results. The theme…

IFSM Young Scientist Assembly

Dr. Michele Conroy was selected as one of the early career researchers to attend the International Federation of Societies for Microscopy Young Scientist Assembly.

Institute of Physics: Three Minute Wonder Competition

PhD student Eileen Courtney travelled to the Royal Institution in London in May, to take part in IOP's Three Minute Wonder Competition. 12 early…

MSI Symposium Sligo 2018

Members of the TEMUL set out for the MSI Symposium in Sligo, from 23rd to 24th April 2018. The symposium gathered attendees from all…

Magnapharm in Jülich and Mainz

TEMUL took a short trip to Forschungszentrum Jülich, Germany, and Johannes Gutenberg University Mainz, Germany, to collect diffraction data on coronene and indomethacin specimens.

Horizon 2020 MagnaPharm Project Undergoes First Technical Action Review

Members TEMUL working on the MagnaPharm project travelled to Bristol to participate in the first technical action review by the European Commission.

First Visualisation of Crystal Growth from Organic Molecules

Organic molecules were formed and grown in a liquid environment and characterised using the DENSsolutions Ocean In Situ system for Liquid Phase Electron Microscopy (LPEM).
“Using LCEM (liquid cell electron microscopy) it has been possible for the first time to capture early-stage nucleation events of organic molecular crystals used as APIs (active pharmaceutical ingredients),” said Dr Jennifer Cookman from the Bernal Institute at the University of Limerick and lead researcher for this study. “The importance of this method is that we can begin to understand how one crystal structure forms over another and, even more importantly, how these early-stage nucleation events manifest. We can also compare/contrast with classical nucleation theory and other crystal growth theories.” The molecule studied, flufenamic acid, is a COX-inhibitor that acts as an anti-inflammatory. With increased study of this molecule, which is used in the pharmaceutical industry, researchers can potentially fine-tune its action as a medicinal drug and reduce its side-effects. What’s more, the molecular crystalline state is widely used across many industries; including electronics and agrochemicals. This research represents the first steps to analysing molecular crystal growth of not just flufenamic acid, but other molecules with implications for improvements in other industries. The Ocean LPEM system’s unique ability to perform transmission electron microscopy in a liquid ethanol environment was essential for this research. Dr Cookman adds that by “using the…
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